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[140]. To date, all other types of DGI and DD have been associated with mutations in DSPP. It should be noted, that with the exception of the abnormal collagen in DGI type I, all of the other forms are associated with abnormalities in an IDP. Due to the collagen anomaly we suggest that the IDPs similarly contribute to the phenotype in DGI type I as the IDPs bind to specific sites on the collagen m
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Tatistically significant in WT mice, but did not achieve significance in the SP-A-/- mice. These proteins appear to play a role in asthma, chronic obstructive pulmonary disease, and other inflammatory lung diseases [37-39] although their exact action in these conditions is not known. Annexin A1 had a similar pattern, increasing with infection in both strains, but only reaching significance in the
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Ficient RNA replication resulting in almost 200000 RNA copies [27] from each RNAFicient RNA replication resulting in almost 200000 RNA copies [27] from each RNA template . Although replication-deficient particles provide a high level of safety, there is still a marginal risk of the generation of replication-proficient particles through nonhomologous recombination. To minimize this risk, spli
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