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One MAPKKK tagged with the myc epitope and the other tagged with HATAP were exposed to osmostress of 0.6 M KCl (B) or oxidative stress of 0.73 mM H2O2 (C), and their cell lysate was subjected to affinity purification with IgG epharose, followed by immunoblotting with anti-myc and anti-HA antibodies. The strains expressing no HATAP-tagged MAPKKK served as negative controls (wis4+ and win1+). Bottom
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Compact bowel, liver, prostate, thyroid, lung and urinary tract according to the SEER information [23,24]. Among lung carcinoids, excess threat of breast and prostate cancers was reported [24]. In the Swedish study, improved threat of metachronous second cancer after diagnosis of carcinoid was noticed in little intestine, prostate, skin,PLOS One | www.plosone.orgSecond Cancers in Neuroendocrine Tu
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N. Roc2KG mutant animals develop normally, and we could detect no obvious phenotype, except for a slight reduction in female fecundity. The Cul5 locus is simpler than that of Roc2, and the Cul5 transcript includes 7 exons and 6 introns. We identified a P element (Cul5EY) that is inserted into the second exon of Cul5 at amino acid D346 of the predicted open reading frame (Fig. 7B). RT-PCR analysis
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